Biphasic model of cartilage

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August undefined, 2024

WebFeb 1, 1980 · We also concluded that 1) a nonlinearly permeable biphasic model, where the permeability function is given by an experimentally determined empirical law: k = A(p) … WebAug 1, 2012 · Mechanical behavior of cartilage is then described by the biphasic or continuous poro-elastic model that describes the mechanical interactions of the different phases (Donzelli & Spilker, 1998). From the …

A numerical model for fibril remodeling in articular cartilage

WebThe accumulation of MMPs in osteoarthritic cartilage may have a role in the biphasic progression of OA-related pain. Temporal association of changes in ECS and MMPs expression shows a potential therapeutic approach that utilizes the concept of combining indirect ECS-mediated MMP inhibition and ECS modulation of pain transduction. WebJun 1, 1999 · Cartilage mechanical function relies on a composite structure of a collagen fibrillar network entrapping a proteoglycan matrix. Previous biphasic or poroelastic models of this tissue, which have approximated its composite structure using a homogeneous solid phase, have experienced difficulties in describing measured material responses. … descendants of john and priscilla alden

Computational Modelling for Managing Pathways to Cartilage

WebApr 14, 2024 · 5 Using Models to Investigate Pathways to Cartilage Failure. Synovial joint lubrication is one of the key roles of articular cartilage. Synovial joints can experience very small frictional force, with initial friction coefficient ranging from 0.005 to 0.02, while bearing extremely large mechanical stress [ 41, 42 ]. WebApr 21, 2009 · In particular, this model can predict the transition of Poisson’s ratio from very low values in compression (∼ 0.02) to very high values in tension (∼ 2.0) ⁠. Most of these phenomena cannot be explained when using only three orthogonal fiber bundles to describe the tissue matrix, a common modeling assumption used to date. WebNational Center for Biotechnology Information descendants of jamestown colony

The mechanical properties of tibiofemoral and patellofemoral …

WebMar 1, 2024 · The present study for the first time developed a multiscale computational modelling approach that coupled a subject-specific musculoskeletal MBD model of the body and a detailed finite element model of the natural hip joint with biphasic articular cartilage, which enabled the non-invasive evaluation of the time-dependant, nonlinear and solid ... WebBiphasic Theory is a mechanical model developed by Van C. Mow and coworkers for soft tissue, especially articular cartilage, based on Poromechanics. The mechanical behavior of many soft tissues can be best understood by considering it as a multiphasic material. In biphasic theory, the two principle phases are the solid matrix phase and the movable … chrysler dodge anchorage alaskaWebApr 24, 2024 · The relative scarcity of 3-D constitutive models of cartilage speaks to the challenges of capturing the tissue’s complex behavior in a computation model. Existing 3-D, large-strain FE models of articular cartilage use single-phase (e.g., [31, 87, 88]), biphasic, and multi-phasic models, some at considerable computational cost. descendants of jefferson and hemings

"WebJan 1, 1987 · A mathematical solution has been obtained for the indentation creep and stress-relaxation behavior of articular cartilage where the tissue is modeled as a layer of … " - Biphasic model of cartilage

Biphasic model of cartilage

Multi-phase, large-strain constitutive models of cartilage for …

WebA novel, self-assembled artificial cartilage-hydroxyapatite conjugate for combined articular cartilage and subchondral bone repair: histopathological analysis of cartilage tissue engineering in rat knee joints WebThe zone of calcified cartilage is the mineralized region of articular cartilage that anchors the hyaline cartilage to the subchondral bone and serves to disperse mechanical forces …

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Webvations suggest that cartilage behaves like a sponge, albeit one that does not allow fluid to flow through it easily. Recognizing that fluid flow and deformation are interde-pendent has led to the modeling of cartilage as a mixture of fluid and solid components [59–61]. This … WebMar 1, 2024 · The present study for the first time developed a multiscale computational modelling approach that coupled a subject-specific musculoskeletal MBD model of the …

WebMar 17, 2024 · (3) Compared with hyperelastic model, the biphasic models may reflect the mechanical characteristics of cartilage thoroughly 31,32,33. Thus, the relaxation or creep experiments need to be ... WebConstitutive Model. We described cartilage as a biphasic continuum î= îS+ î of a porous solid phase îS saturated with a fluid phase îF. We calculated the total Cauchy stress as [7,8] Ë=− L ÷+2 éS ô S !ΨS ! S ôS T=− L ÷+ Ë E S, (1) where L is the fluid pressure, ÷ is the identity, éS is the partial density

WebApr 14, 2024 · Articular cartilage is a hydrated macromolecular composite mainly composed of type II collagen fibrils and the large proteoglycan, aggrecan. Aggrecan is a key determinant of the loadLoad bearing and energy dissipation functions of cartilageCartilage. ... Soulhat J, Buschmann MD, Shirazi-Adl A (1999) A fibril-network-reinforced biphasic … WebNov 25, 2011 · The biphasic model is the most traditional model of articular cartilage and other fluid-saturated tissue which takes the interstitial fluid movement into account (Mow et al., 1980). In the biphasic theory, the solid matrix and fluid are assumed to be intrinsically incompressible and nondissipative.

WebApr 1, 2001 · The biphasic poroviscoelastic (BPVE) model is a mathematical model for articular cartilage, which describes the apparent viscoelasticity exhibited by the tissue …

WebApr 1, 2024 · This biphasic theory models AC as composite materials consisting of a solid phase (solid like components of the cartilage, proteoglycans, collagen, cells and lipids … chrysler dodge canton ga descendants of john lauriston knellerWebIt seems that a mechanobiological process drives the remodeling of newborn collagen fibrils with maturation. Therefore, the goal of the present study was to develop a collagen fibril remodeling algorithm that describes the unique collagen fibril organization in a 3D knee model. Method: A fibril-reinforced, biphasic cartilage model was used with ... chrysler dodge anniston alWebThe content of glycosaminoglycan in intervertebral soft tissues and the permeability of cartilage endplates are two critical factors that affect the fluid-dependent viscoelastic responses of intervertebral discs. ... Four biphasic swelling-based finite element models are developed and quantitatively validated. Four quasi-static test protocols ... chrysler dodge bayers lakeWebFrom the experimental results and the biphasic poroviscoelastic theory, we found that frictional drag associated with interstitial fluid flow and fluid pressurization are the dominant mechanisms of load support in the intact specimens, i.e. the flow-dependent mechanisms alone were sufficient to describe normal articular cartilage compressive ... descendants of john jacob astorhttp://web.mit.edu/cortiz/www/3.052/3.052CourseReader/27_BiomechanicsofCartilage.pdf chrysler dodge and jeep san angelo txWebRevised model for biphasic contacts Other authors Tribological and material properties for cartilage of and throughout the bovine stifle: … descendants of john hancock