WebSep 22, 2016 · Thyroid transcription factor 1 (TTF1) is a master regulatory transcription factor for tissue-specific genes. 1 TTF1 is mainly expressed in thyroid and lung during embryogenesis and it plays a physiologic role in their development and morphogenesis. 2 In normal lung, TTF1 plays a decisive role in the maintenance of the functions of terminal … WebGEP PDNECs showed a higher aTS for CDX2 and lower aTS for TTF1 and ISL1, compared to that of lung PDNECs (Student's t-test, p < 0.001). SmCC had a higher aTS for TTF1 and ISL1 (p < 0.001) and lower aTS for CDX2 (p < 0.002) than that of LCNEC. Conclusions: CDX2 and TTF1 demonstrate potential utility in suggesting the primary site of PDNEC.
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WebDec 6, 2024 · Two multiplexed IHC assays were developed, for diagnosis and immunophenotyping including TTF1, p40, PD-L1, and pan-Keratin antibodies, and for molecular profiling panel including ALK, ROS1 and ... WebPatients were divided based on level of expression into one of the two groups "low" (under cut off) or "high" (over cut off). X-axis shows time for survival (years) and y-axis shows the probability of survival, where 1.0 corresponds to 100 percent. Read more. TTF1 is not prognostic in prostate cancer. crysoleucas
Anti-TTF-1/Thyroid Transcription Factor 1/NKX2-1 Antibody
WebMay 21, 2024 · TTF1 and p63 expression data were extracted from the hospital information system and merged with registry data to calculate progression‑free survival (PFS) and overall survival (OS) rates. A cohort of 345 patients with adenocarcinoma (ADC) or squamous cell carcinoma (SCC) exhibited similar erlotinib efficacies when TTF1 and p63 … WebTTF1 is a tissue-specific transcription factor which is often use by pathologist to determine the origin (thyroid, lung, or diencephalon) of tumors or to differentiate lung adenocarci-noma from squamous cell carcinoma. TTF1 staining was per-formed using Ventana automates with the 8G7 G3/1 clone WebFeb 6, 2024 · Context.—. Distinction between Merkel cell carcinoma (MCC) and pulmonary small cell carcinoma (PSmCC) can be challenging, even with the aid of immunohistochemistry (IHC) analysis of CK20 and TTF1, as these tumors occasionally lack classic immunophenotypes (CK20+/TTF1− in MCC and CK20−/TTF1+ in … crysoon